General Information

  • ID:  hor004308
  • Uniprot ID:  A0A8J5MMN2
  • Protein name:  Tachykinin-related peptide
  • Gene name:  NA
  • Organism:  Homarus americanus (American lobster)
  • Family:  Tachykinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  PSGFLGMR
  • Length:  8(38-45)
  • Propeptide:  MVRACTWAVLLGVVVVMGVVSAAGEGQDTPQDRERRAPSGFLGMRGKKDASTALDDNTAASEYSSLPDPYPLYGLRDNNLPMLFAVPWKTKKAPSGFLGMRGKKSDEEVFSDATADNDLEILLKRAPSGFLGMRGKKAPSGFLGMRGKKAPSGFLGMRGKKYYDDDSDMDAYIQALTAVVDGQQQQKRAPSGFLGMRGKKAYYSENPDEEISMTGVDKRTPSGFLGVRCSLHSALPCLKIIPRAVIPA
  • Signal peptide:  MVRACTWAVLLGVVVVMGVVSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004308_AF2.pdbhor004308_ESM.pdb

Physical Information

Mass: 98906 Formula: C38H61N11O10S
Absent amino acids: ACDEHIKNQTVWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: 10 Boman Index: -619
Half-Life: >20 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: ? Aliphatic Index 48.75
Instability Index: 2340 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18304551
  • Title:  Mass Spectral Characterization of Peptide Transmitters/Hormones in the Nervous System and Neuroendocrine Organs of the American Lobster Homarus Americanus